Gene3D - A database of CATH structural domain data projected onto the major sequence repositories. The files made available here are the copyright of Gene3D. Whilst we encourage you to download these files and to use them for research we do not permit the resale of this data and if you wish to display it within your own resource please acknowledge the latest NAR database issue publication. All files are gzipped for compression. the files are quite large ~1-2 GB compressed. If you would like subsets of this data please contact us at gene3d.contact@gmail.com Files ----- Release information: current_release_version.txt gives the current release number and the corresponding CATH release code. FASTA files: * SUPERFAMILY_FASTA_FILES/[superfamily].fa.gz - a FASTA file of the domains in that superfamily. HMM files: * gene3d_classified.hmm.gz - the set of HMMs representing the current release of CATH concatenated into a single file. * model_to_family_map.csv.gz - a table mapping model names to the superfamily they represent. * arch_schema_cath.tsv.gz - a table of uniprot annotations for CATH Columns of this file are: Uniprot accession Uniprot ID domain identifier within the sequence (c) indicates continuous domain (p) indicates a unique id to link discontiguous domains Family Accession AA Start AA Stop * ensembl_domains.txt.gz - domain annotations for Ensembl species. In regions not assigned CATH domains we have added in Pfam and superfamily resource domains. However we encourage people to visit the home pages of these resources to get the most up to date and comprehensive assignments for these external resources. Columns of this file are: Unique Id of the protein sequence Gene accession Protein accession Family code Regions of the sequence assigned to this domain family (after domain boundary resolution by domain finder) Taxon ID The FunFam sub-classification of the domain family Regions of the sequence assigned to this domain family Protein sequence length Whether the domain family passes the threshold for assignment to the funfam